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Dr. Martin Adelmann
Ms. Raquel Cabana
Dr. L. Scott Cram
Dr. Madhu Dikshit
Dr. Sumeet Gujral
Mr. Michael Keeney
Dr. Awtar Krishan
Dr. Mike Ormerod
Dr. Vincent Shankey
Dr. Arvinder Singh
Dr. Ranbir Sobti
Dr. Vivek Tanavde
Dr. William G. Telford
Dr. Rakesh Singal
Mrs. Veena Kapoor
Mr. Ron Hamelik
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Core Faculty
Dr. Vivek Tanavde
Vivek Tanavde received his Ph.D. from Cancer Research Institute, Mumbai. His
Post Doctoral training was at Johns Hopkins University School of Medicine, Baltimore, where he studied expansion of CD34+ stem cells from human
umbilical cord blood. He also optimized conditions for retroviral and lentiviral transduction of stem cells and participated in generation of
preclinical data on expansion of Peripheral Blood Stem Cells (PBSC), purged with 4-hydroxycyclophosphamide. From 2002 -2006, he was a Research
Scientist heading the Hematopoietic Stem Cell Laboratory at Reliance Life Sciences, Mumbai. His laboratory studied the differentiation of mesenchymal stem cells into different tissues. His laboratory also provided clinical flow cytometry support to various hospitals in India in the form of single platform CD4/CD8 assays & CD34 enumeration from cord blood & PBSC harvests. Currently Vivek is a Research Scientist at the Bioinformatics Institute located in the Biopolis hub of Singapore. His research now focuses on creation of a stem cell knowledgebase which integrates gene expression data from different platforms like microarray, massively parallel signature sequencing(MPSS), microscopy & flow cytometry.
Lecture
Mesenchymal Stem Cells:
Their Biology & Clinical Applications
Mesenchymal Stem Cells (MSC) are multipotent cells that can be induced in vitro and in vivo to differentiate into a variety of mesenchymal tissues, including bone, cartilage, fat, and muscle. Studies reporting the multipotentiality of marrow MSC suggest clinical applications in the treatment of tissue damage or degenerative diseases. Considerable progress has been made towards characterizing the cell surface antigenic profile of MSC populations using fluorescence activated cell sorting (FACS) and magnetic bead sorting techniques. A single marker that definitively delineates MSC has yet to be identified. However, there is general agreement that MSC lack typical hematopoietic antigens, like CD45, CD34 and CD14.
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